Assay Detail
Binding
CHEMBL4392136
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-Way100635 from recombinant human 5HT1A receptor stably expressed in CHO cells measured after 90 mins by microbeta scintillation counting method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D<sub>1</sub> Receptor Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.53 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4277264 | — | — | 1 | 5.92 |
| CHEMBL4469848 | — | — | 1 | 5.60 |
| CHEMBL4466483 | — | — | 1 | 5.43 |
| CHEMBL4572614 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4277264 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL4469848 | — | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL4466483 | — | Ki | = | 3700.0 | nM | 5.43 |
| CHEMBL4572614 | — | Ki | = | 6900.0 | nM | 5.16 |