Assay Detail
Functional
CHEMBL4393515
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Cytotoxicity against human HL60 cells measured after 72 hrs by CCK8 assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic Tigliane Diterpenoids from Croton damayeshu.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.57 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 7.10 |
| CHEMBL2375779 | — | — | 1 | 5.75 |
| CHEMBL4547006 | — | — | 1 | 5.62 |
| CHEMBL4466266 | — | — | 1 | 4.72 |
| CHEMBL4514467 | — | — | 1 | 4.64 |
| CHEMBL4444562 | — | — | 1 | - |
| CHEMBL4534646 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL2375779 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL4547006 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL4466266 | — | IC50 | = | 18900.0 | nM | 4.72 |
| CHEMBL4514467 | — | IC50 | = | 22700.0 | nM | 4.64 |
| CHEMBL4444562 | — | IC50 | - | — | - | |
| CHEMBL4534646 | — | IC50 | - | — | - |