Assay Detail
Functional
CHEMBL4396495
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Antiproliferative activity against human C32 cells assessed as reduction in cell viability incubated for 72 hrs by WST1 assay
19
Total Activities
19
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | C32 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Betulin-1,4-quinone hybrids: Synthesis, anticancer activity and molecular docking study with NQO1 enzyme.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 19 | 5.37 | 5.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4563912 | — | — | 1 | 5.98 |
| CHEMBL4454208 | — | — | 1 | 5.94 |
| CHEMBL4575987 | — | — | 1 | 5.90 |
| CHEMBL4476166 | — | — | 1 | 5.88 |
| CHEMBL4436634 | — | — | 1 | 5.76 |
| CHEMBL4535754 | — | — | 1 | 5.19 |
| CHEMBL4550434 | — | — | 1 | 4.90 |
| CHEMBL4573652 | — | — | 1 | 4.86 |
| CHEMBL4449506 | — | — | 1 | 4.64 |
| CHEMBL4458328 | — | — | 1 | 4.61 |
| CHEMBL23236 | BETULIN | — | 1 | - |
| CHEMBL4453150 | — | — | 1 | - |
| CHEMBL318782 | Dichlon | — | 1 | - |
| CHEMBL1096668 | — | — | 1 | - |
| CHEMBL132160 | — | — | 1 | - |
| CHEMBL4472808 | — | — | 1 | - |
| CHEMBL4444026 | — | — | 1 | - |
| CHEMBL4570615 | — | — | 1 | - |
| CHEMBL4471946 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4563912 | — | IC50 | = | 1040.0 | nM | 5.98 |
| CHEMBL4454208 | — | IC50 | = | 1140.0 | nM | 5.94 |
| CHEMBL4575987 | — | IC50 | = | 1270.0 | nM | 5.90 |
| CHEMBL4476166 | — | IC50 | = | 1330.0 | nM | 5.88 |
| CHEMBL4436634 | — | IC50 | = | 1720.0 | nM | 5.76 |
| CHEMBL4535754 | — | IC50 | = | 6520.0 | nM | 5.19 |
| CHEMBL4550434 | — | IC50 | = | 12650.0 | nM | 4.90 |
| CHEMBL4573652 | — | IC50 | = | 13830.0 | nM | 4.86 |
| CHEMBL4449506 | — | IC50 | = | 22920.0 | nM | 4.64 |
| CHEMBL4458328 | — | IC50 | = | 24670.0 | nM | 4.61 |
| CHEMBL23236 | BETULIN | IC50 | - | — | - | |
| CHEMBL4453150 | — | IC50 | - | — | - | |
| CHEMBL318782 | Dichlon | IC50 | - | — | - | |
| CHEMBL1096668 | — | IC50 | - | — | - | |
| CHEMBL132160 | — | IC50 | - | — | - | |
| CHEMBL4472808 | — | IC50 | - | — | - | |
| CHEMBL4444026 | — | IC50 | - | — | - | |
| CHEMBL4570615 | — | IC50 | - | — | - | |
| CHEMBL4471946 | — | IC50 | - | — | - |