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Assay Detail

CHEMBL4396985

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Downregulation of VEGF protein level in human Hep3B cells after 8 hrs by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Hep 3B2
Confidence 1 — Organism
Curated By Autocuration

Target

Hep 3B2 (CHEMBL4296437)
Type CELL-LINE
Organism Homo sapiens

Publication

Small-Molecule Modulators of the Hypoxia-Inducible Factor Pathway: Development and Therapeutic Applications.
Li Z, You Q, Zhang X.
J Med Chem (2019) 62 : 5725 -5749
PubMed 30682255 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1089316 CHAETOCIN 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1089316 CHAETOCIN IC50 = 100.0 nM 7.00