Assay Detail
Binding
CHEMBL4398443
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Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Estrogen signaling: An emanating therapeutic target for breast cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.30 | 10.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137392 | — | — | 1 | 10.33 |
| CHEMBL137692 | — | — | 1 | 10.05 |
| CHEMBL275331 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137392 | — | IC50 | = | 0.047 | nM | 10.33 |
| CHEMBL137692 | — | IC50 | = | 0.089 | nM | 10.05 |
| CHEMBL275331 | — | IC50 | = | 30.0 | nM | 7.52 |