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Assay Detail

CHEMBL4398451

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ERbeta in human MCF7 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type MCF7
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Estrogen receptor beta (CHEMBL242)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Estrogen signaling: An emanating therapeutic target for breast cancer treatment.
Saha T, Makar S, Swetha R, Gutti G, Singh SK.
Eur J Med Chem (2019) 177 : 116 -143
PubMed 31129450 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.75 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL520107 1 5.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL520107 Ki = 1800.0 nM 5.75