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Assay Detail

CHEMBL4398465

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Binding
Inhibition of Flu-BakBH3 peptide binding to recombinant human Bcl-xL after 15 mins by fluorescence polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bcl-2-like protein 1 (CHEMBL4625)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The chemical biology of apoptosis: Revisited after 17 years.
Yang S, Mao Y, Zhang H, Xu Y, An J, Huang Z.
Eur J Med Chem (2019) 177 : 63 -75
PubMed 31129454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.18 6.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1272170 1 6.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1272170 Ki = 660.0 nM 6.18