Assay Detail
Binding
CHEMBL4399014
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Inhibition of steroid sulfatase (unknown origin)
9
Total Activities
9
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Sulfamates in drug design and discovery: Pre-clinical and clinical investigations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.84 | 9.00 |
| INH | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3622010 | — | — | 1 | 9.00 |
| CHEMBL4436186 | — | — | 1 | 9.00 |
| CHEMBL4517286 | — | — | 1 | 9.00 |
| CHEMBL4442535 | — | — | 1 | 8.62 |
| CHEMBL122708 | EMATE | — | 1 | 8.10 |
| CHEMBL11185 | — | — | 1 | 7.52 |
| CHEMBL136112 | — | — | 1 | 6.01 |
| CHEMBL84380 | — | — | 1 | 5.47 |
| CHEMBL4542407 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3622010 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4436186 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4517286 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4442535 | — | IC50 | = | 2.4 | nM | 8.62 |
| CHEMBL122708 | EMATE | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL11185 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL136112 | — | IC50 | = | 970.0 | nM | 6.01 |
| CHEMBL84380 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL4542407 | — | INH | >= | 2.0 | nM | - |