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Assay Detail

CHEMBL4399504

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of SMS2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Malabaricone C as Natural Sphingomyelin Synthase Inhibitor against Diet-Induced Obesity and Its Lipid Metabolism in Mice.
Othman MA, Yuyama K, Murai Y, Igarashi Y, Mikami D, Sivasothy Y, Awang K, Monde K.
ACS Med Chem Lett (2019) 10 : 1154 -1158
PubMed 31413799 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.82 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL445177 GINGKOLIC ACID 1 5.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL445177 GINGKOLIC ACID IC50 = 1500.0 nM 5.82