Assay Detail
Binding
CHEMBL4400854
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DOHH (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Medicinal chemistry of metal chelating fragments in metalloenzyme active sites: A perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL70927 | DEFERIPRONE | 4.0 | 1 | 5.30 |
| CHEMBL39879 | DIPYRIDYL | — | 1 | 5.30 |
| CHEMBL556 | DEFEROXAMINE | 4.0 | 1 | 5.30 |
| CHEMBL245416 | L-MIMOSINE | — | 1 | 5.30 |
| CHEMBL1413 | CICLOPIROX | 4.0 | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL70927 | DEFERIPRONE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL39879 | DIPYRIDYL | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL556 | DEFEROXAMINE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL245416 | L-MIMOSINE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1413 | CICLOPIROX | IC50 | = | 5000.0 | nM | 5.30 |