Assay Detail
Functional
CHEMBL4401389
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Cytotoxicity in human MOLM14 cells assessed as inhibition of cellular viability after 72 hrs by CellTiter-Glo luminescent assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLM-14 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Virtual Screening Identifies Irreversible FMS-like Tyrosine Kinase 3 Inhibitors with Activity toward Resistance-Conferring Mutations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.85 | 8.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4553725 | — | — | 1 | 8.11 |
| CHEMBL4442997 | — | — | 1 | 7.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4553725 | — | IC50 | = | 7.8 | nM | 8.11 |
| CHEMBL4442997 | — | IC50 | = | 26.4 | nM | 7.58 |