Assay Detail
Functional
CHEMBL4401871
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV-1-derived Ebolavirus pseudoparticle infected in human TZM-bl cells after 48 hrs by beta-gal based reporter assay
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Ebolavirus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.62 | 7.30 |
| IC80 | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4441098 | — | — | 2 | 7.30 |
| CHEMBL1655 | TOREMIFENE | 4.0 | 2 | 7.05 |
| CHEMBL4536298 | — | — | 2 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4441098 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL1655 | TOREMIFENE | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL4536298 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL4536298 | — | IC80 | = | 50.0 | uM | - |
| CHEMBL4441098 | — | IC80 | = | 0.39 | uM | - |
| CHEMBL1655 | TOREMIFENE | IC80 | = | 3.0 | uM | - |