Assay Detail
Functional
CHEMBL4403203
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 3B infected in human C8166 cells
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Synthetic routes and structure-activity relationships (SAR) of anti-HIV agents: A key review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 10.81 | 10.92 |
| IC50 | 1 | 6.12 | 6.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1643094 | — | — | 1 | 10.92 |
| CHEMBL1643090 | — | — | 1 | 10.92 |
| CHEMBL1643092 | — | — | 1 | 10.60 |
| CHEMBL4517119 | — | — | 1 | 6.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1643094 | — | EC50 | = | 0.012 | nM | 10.92 |
| CHEMBL1643090 | — | EC50 | = | 0.012 | nM | 10.92 |
| CHEMBL1643092 | — | EC50 | = | 0.025 | nM | 10.60 |
| CHEMBL4517119 | — | IC50 | = | 760.0 | nM | 6.12 |