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Assay Detail

CHEMBL4403208

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV1 3B infected in human CEM cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Synthetic routes and structure-activity relationships (SAR) of anti-HIV agents: A key review.
Huang YM, Alharbi NS, Sun B, Shantharam CS, Rakesh KP, Qin HL.
Eur J Med Chem (2019) 181 : 111566 -111566
PubMed 31401538 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.54 6.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL242378 1 6.64
CHEMBL395532 1 6.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL242378 EC50 = 230.0 nM 6.64
CHEMBL395532 EC50 = 370.0 nM 6.43