Assay Detail
Functional
CHEMBL4403220
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against wild type HIV1 3B infected in human MT4 cells using [3H]dGTP by radio-labelled binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Synthetic routes and structure-activity relationships (SAR) of anti-HIV agents: A key review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.24 | 7.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48427 | — | — | 1 | 7.36 |
| CHEMBL505380 | — | — | 1 | 7.28 |
| CHEMBL296589 | — | — | 1 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48427 | — | IC50 | = | 44.0 | nM | 7.36 |
| CHEMBL505380 | — | IC50 | = | 53.0 | nM | 7.28 |
| CHEMBL296589 | — | IC50 | = | 82.0 | nM | 7.09 |