Assay Detail
Functional
CHEMBL4403370
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Antileishmanial activity against Leishmania mexicana intracellular amastigotes infected in J774 macrophages assessed as reduction in parasite viability after 72 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania mexicana |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multi-target drugs active against leishmaniasis: A paradigm of drug repurposing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL561057 | SQ109 | 2.0 | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL561057 | SQ109 | IC50 | = | 11.0 | nM | 7.96 |