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Assay Detail

CHEMBL4404060

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Aliivibrio fischeri LuxR by luminescence method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Aliivibrio fischeri
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Transcriptional activator protein LuxR (CHEMBL5351)
Type SINGLE PROTEIN
Organism Aliivibrio fischeri

Publication

Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria.
Chbib C.
Bioorg Med Chem (2020) 28 : 115282 -115282
PubMed 31918952 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4527540 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4527540 IC50 = 130.0 nM 6.89