Assay Detail
Binding
CHEMBL4406927
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human M3 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeted Treatments for Chronic Obstructive Pulmonary Disease (COPD) Using Low-Molecular-Weight Drugs (LMWDs).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.80 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3039518 | BATEFENTEROL | 2.0 | 1 | 8.80 |
| CHEMBL4297483 | NAVAFENTEROL | 2.0 | 1 | 8.80 |
| CHEMBL3916700 | LAS190792 | 1.0 | 1 | 8.80 |
| CHEMBL4465556 | — | — | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3039518 | BATEFENTEROL | IC50 | = | 1.585 | nM | 8.80 |
| CHEMBL4297483 | NAVAFENTEROL | IC50 | = | 1.585 | nM | 8.80 |
| CHEMBL3916700 | LAS190792 | IC50 | = | 1.585 | nM | 8.80 |
| CHEMBL4465556 | — | IC50 | = | 1.585 | nM | 8.80 |