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Assay Detail

CHEMBL4406928

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at human beta2 adrenoceptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-2 adrenergic receptor (CHEMBL210)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeted Treatments for Chronic Obstructive Pulmonary Disease (COPD) Using Low-Molecular-Weight Drugs (LMWDs).
Ti H, Zhou Y, Liang X, Li R, Ding K, Zhao X.
J Med Chem (2019) 62 : 5944 -5978
PubMed 30682248 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 4 9.60 9.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3039518 BATEFENTEROL 2.0 1 9.60
CHEMBL4297483 NAVAFENTEROL 2.0 1 9.60
CHEMBL3916700 LAS190792 1.0 1 9.60
CHEMBL4465556 1 9.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3039518 BATEFENTEROL EC50 = 0.2512 nM 9.60
CHEMBL4297483 NAVAFENTEROL EC50 = 0.2512 nM 9.60
CHEMBL3916700 LAS190792 EC50 = 0.2512 nM 9.60
CHEMBL4465556 EC50 = 0.2512 nM 9.60