Assay Detail

CHEMBL4408775

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Binding

Binding affinity to SNARK (unknown origin)

ChEMBL ↗

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Target

NUAK family SNF1-like kinase 2 (CHEMBL5698) ↗

Open DB target context

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Loading context

NUAK family SNF1-like kinase 2 (CHEMBL5698) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NUAK family SNF1-like kinase 2

CHEMBL5698

Anchored from Assay target.

Protein identity NUAK family SNF1-like kinase 2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

NUAK family SNF1-like kinase 2 (CHEMBL5698) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Cyclin dependent kinase (CDK) inhibitors as anticancer drugs: Recent advances (2015-2019).

Sánchez-Martínez C, Lallena MJ, Sanfeliciano SG, de Dios A.
Bioorg Med Chem Lett (2019) 29 : 126637 -126637
PubMed 31477350 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	9.15	9.15

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3904602	LEROCICLIB	3.0	1	9.15

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3904602	LEROCICLIB	Kd	=	0.7	nM	9.15