Assay Detail
Functional
CHEMBL4408804
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Antiproliferative activity against human HL60 cells after 72 hrs by CellTiter-Glo assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cyclin dependent kinase (CDK) inhibitors as anticancer drugs: Recent advances (2015-2019).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.98 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4436535 | — | — | 1 | 8.52 |
| CHEMBL4582951 | — | — | 1 | 8.10 |
| CHEMBL4441405 | — | — | 1 | 7.89 |
| CHEMBL3603847 | — | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4436535 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4582951 | — | EC50 | = | 8.0 | nM | 8.10 |
| CHEMBL4441405 | — | EC50 | = | 13.0 | nM | 7.89 |
| CHEMBL3603847 | — | EC50 | = | 38.0 | nM | 7.42 |