Assay Detail
Binding
CHEMBL4409335
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of kappa opioid receptor in guinea pig brain membranes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Brain |
| Subcellular | Membranes |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress in the development of more effective and safer analgesics for pain management.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.91 | 6.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL299031 | — | — | 1 | 6.91 |
| CHEMBL61630 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL299031 | — | Ki | = | 123.0 | nM | 6.91 |
| CHEMBL61630 | — | Ki | > | 1000.0 | nM | - |