Assay Detail
Binding
CHEMBL4411348
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tyrosinase in mouse B16 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of Melanogenesis: An Updated Review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.13 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL221291 | — | — | 1 | 6.52 |
| CHEMBL4445400 | — | — | 1 | 6.10 |
| CHEMBL43065 | OXYRESVERATROL | — | 1 | 5.77 |
| CHEMBL455619 | MULBERROSIDE A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL221291 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4445400 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL43065 | OXYRESVERATROL | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL455619 | MULBERROSIDE A | IC50 | > | 100000.0 | nM | - |