Assay Detail
Binding
CHEMBL4411352
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tyrosinase (unknown origin) assessed as reduction in diphenolase activity
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of Melanogenesis: An Updated Review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.82 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3810334 | — | — | 1 | 5.55 |
| CHEMBL4572517 | — | — | 1 | 4.90 |
| CHEMBL287556 | KOJIC ACID | — | 1 | 4.70 |
| CHEMBL4466751 | — | — | 1 | 4.58 |
| CHEMBL4556868 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3810334 | — | IC50 | = | 2790.0 | nM | 5.55 |
| CHEMBL4572517 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL4466751 | — | IC50 | = | 26200.0 | nM | 4.58 |
| CHEMBL4556868 | — | IC50 | = | 42800.0 | nM | 4.37 |