Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4411363

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human tyrosinase after 120 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tyrosinase (CHEMBL1973)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibitors of Melanogenesis: An Updated Review.
Pillaiyar T, Namasivayam V, Manickam M, Jung SH.
J Med Chem (2018) 61 : 7395 -7418
PubMed 29763564 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.02 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL66879 COUMARIC ACID 1 5.52
CHEMBL146816 METHYL P-HYDROXYCINNAMATE 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL66879 COUMARIC ACID IC50 = 3000.0 nM 5.52
CHEMBL146816 METHYL P-HYDROXYCINNAMATE IC50 = 30000.0 nM 4.52