Assay Detail

CHEMBL4411520

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Functional

Cytotoxicity against ALL/AML patient derived primary leukemia cells after 24 hrs by LDH release assay

ChEMBL ↗

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Target

Leukemia cell (CHEMBL614844) ↗

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Primary target Leukemia cell

CHEMBL614844

Anchored from Assay target.

Protein identity Leukemia cell

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Leukemia cell
Confidence	1 — Organism
Curated By	Autocuration

Target

Leukemia cell (CHEMBL614844) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus.

Nuutinen T.
Eur J Med Chem (2018) 157 : 198 -228
PubMed 30096653 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.85	4.85

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1096927	LEVOMENOL	2.0	1	4.85

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1096927	LEVOMENOL	IC50	=	14000.0	nM	4.85