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Assay Detail

CHEMBL4412105

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human JNK3 using ATF2 as substrate by [gamma-33P]-ATP assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 10 (CHEMBL2637)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chemistry-oriented synthesis (ChOS) and target deconvolution on neuroprotective effect of a novel scaffold, oxaza spiroquinone.
Venkanna A, Cho KH, Dhorma LP, Kumar DN, Hah JM, Park HG, Kim SY, Kim MH.
Eur J Med Chem (2019) 163 : 453 -480
PubMed 30530196 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.11 6.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL210618 1 6.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL210618 IC50 = 770.0 nM 6.11