Assay Detail
Binding
CHEMBL4415152
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Inhibition of H3R (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.74 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4585201 | — | — | 1 | 9.30 |
| CHEMBL4548796 | — | — | 1 | 9.12 |
| CHEMBL49532 | — | — | 1 | 8.70 |
| CHEMBL4450928 | — | — | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4585201 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL4548796 | — | Ki | = | 0.75 | nM | 9.12 |
| CHEMBL49532 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL4450928 | — | Ki | = | 14.0 | nM | 7.85 |