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Assay Detail

CHEMBL4415740

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV-1 3B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research.
Hodon J, Borkova L, Pokorny J, Kazakova A, Urban M.
Eur J Med Chem (2019) 182 : 111653 -111653
PubMed 31499360 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL125 MILTEFOSINE 4.0 1 8.00
CHEMBL168 OLEANOLIC_ACID 1 8.00
CHEMBL169 URSOLIC ACID 2.0 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL125 MILTEFOSINE EC50 = 10.0 nM 8.00
CHEMBL168 OLEANOLIC_ACID EC50 = 10.0 nM 8.00
CHEMBL169 URSOLIC ACID EC50 = 10.0 nM 8.00