Assay Detail
Functional
CHEMBL4416468
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Cytotoxicity against human SKOV3 cells assessed as reduction in cell growth incubated for 5 days by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Sparticolins A-G, Biologically Active Oxidized Spirodioxynaphthalene Derivatives from the Ascomycete <i>Sparticola junci</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.43 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL94657 | PATUPILONE | 3.0 | 1 | 9.55 |
| CHEMBL4558497 | — | — | 1 | 6.52 |
| CHEMBL4464000 | — | — | 1 | 6.22 |
| CHEMBL4446297 | — | — | 1 | - |
| CHEMBL4530492 | — | — | 1 | - |
| CHEMBL4534431 | — | — | 1 | - |
| CHEMBL4551931 | — | — | 1 | - |
| CHEMBL4468015 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL94657 | PATUPILONE | IC50 | = | 0.28 | nM | 9.55 |
| CHEMBL4558497 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4464000 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4446297 | — | IC50 | - | — | - | |
| CHEMBL4530492 | — | IC50 | - | — | - | |
| CHEMBL4534431 | — | IC50 | - | — | - | |
| CHEMBL4551931 | — | IC50 | - | — | - | |
| CHEMBL4468015 | — | IC50 | - | — | - |