Assay Detail
Functional
CHEMBL4416672
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Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.40 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4435139 | — | — | 1 | 5.89 |
| CHEMBL4458301 | — | — | 1 | 5.70 |
| CHEMBL4449333 | — | — | 1 | 5.35 |
| CHEMBL4460874 | — | — | 1 | 5.28 |
| CHEMBL4568654 | — | — | 1 | 5.11 |
| CHEMBL4570692 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4435139 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4458301 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4449333 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL4460874 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL4568654 | — | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL4570692 | — | IC50 | = | 8500.0 | nM | 5.07 |