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Assay Detail

CHEMBL4419837

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FLAG-tagged DGKa (unknown origin) using lipids and [gamma-32P]-ATP incubated for 15 mins by scintillation counting method
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Diacylglycerol kinase alpha (CHEMBL4105787)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Compositions and methods for treating cancer
(2017)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Inhibition 2 - -
IC50 2 4.88 5.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL267777 RITANSERIN 2.0 2 5.05
CHEMBL259388 2 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL267777 RITANSERIN IC50 = 9000.0 nM 5.05
CHEMBL259388 IC50 = 20000.0 nM 4.70
CHEMBL267777 RITANSERIN Inhibition - % -
CHEMBL259388 Inhibition - % -