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Assay Detail

CHEMBL4420299

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to TFPI (unknown origin) incubated for 1.5 hrs using tracer peptide JBT2271 by competition ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tissue factor pathway inhibitor (CHEMBL3713062)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tfpi inhibitors and methods of use
(2013)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.54 8.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4545581 1 8.54
CHEMBL4473203 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4545581 IC50 = 2.9 nM 8.54
CHEMBL4473203 IC50 >= 4.8 nM -