Assay Detail

CHEMBL4420464

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Cytotoxicity against human Hep3B cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Hep 3B2 (CHEMBL4296437) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Hep 3B2 (CHEMBL4296437) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Hep 3B2

CHEMBL4296437

Anchored from Assay target.

Protein identity Hep 3B2

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Hep 3B2
Confidence	1 — Organism
Curated By	Autocuration

Target

Hep 3B2 (CHEMBL4296437) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Aryl amine substituted quinoxaline used as anticancer drugs

(2017)

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Activity	1	-	-
IC50	1	6.05	6.05

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4460989	—	—	1	6.05
CHEMBL553	ERLOTINIB	4.0	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4460989	—	IC50	=	900.0	nM	6.05
CHEMBL553	ERLOTINIB	Activity		-	—	-