Assay Detail
ADMET
CHEMBL4422000
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Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 72 hrs by CT-Glo cytotoxicity assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel drug targets to overcome de novo drug-resistance in multiple myeloma
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.39 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1413199 | DIPHENADIONE | 2.0 | 1 | 4.52 |
| CHEMBL1186087 | — | — | 1 | 4.25 |
| CHEMBL4474391 | — | — | 1 | - |
| CHEMBL1534034 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1413199 | DIPHENADIONE | IC50 | = | 30100.0 | nM | 4.52 |
| CHEMBL1186087 | — | IC50 | = | 56300.0 | nM | 4.25 |
| CHEMBL4474391 | — | IC50 | = | 136000.0 | nM | - |
| CHEMBL1534034 | — | IC50 | = | 199300.0 | nM | - |