Assay Detail
Binding
CHEMBL4422546
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli assessed as reduction in phosphatase activity using OMFP as substrate in absence of MgCl2 by FITS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of eya2
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.00 | 4.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL858 | EDETIC ACID | 3.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL858 | EDETIC ACID | IC50 | = | 100000.0 | nM | 4.00 |