Assay Detail
Binding
CHEMBL4424467
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant Synechocystis sp. PCC 6803 FBA2 S50A mutant expressed in Escherichia coli BL21 (DE3) using FBP as substrate measured over 5 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Synechocystis sp. PCC 6803 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Fructose-bisphosphate aldolase class 2 (CHEMBL4523320) ↗| Type | SINGLE PROTEIN |
| Organism | Synechocystis sp. (strain PCC 6803 / Kazusa) |
Publication
Design, synthesis and algicides activities of thiourea derivatives as the novel scaffold aldolase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.12 | 5.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4476697 | — | — | 1 | 5.41 |
| CHEMBL1551854 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4476697 | — | Ki | = | 3900.0 | nM | 5.41 |
| CHEMBL1551854 | — | Ki | = | 15200.0 | nM | 4.82 |