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Assay Detail

CHEMBL4425343

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Binding
Inhibition of IDE (unknown origin) assessed as cleavage of Mca-RPPGFSAFK(Dnp)-OH by fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Insulin-degrading enzyme (CHEMBL1293287)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chemical Space of DNA-Encoded Libraries.
Franzini RM, Randolph C.
J Med Chem (2016) 59 : 6629 -6644
PubMed 26914744 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.30 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4556893 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4556893 IC50 = 50.0 nM 7.30