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Assay Detail

CHEMBL4426087

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of activated Protein C (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Vitamin K-dependent protein C (CHEMBL4444)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines.
Hinkes S, Wuttke A, Saupe SM, Ivanova T, Wagner S, Knörlein A, Heine A, Klebe G, Steinmetzer T.
J Med Chem (2016) 59 : 6370 -6386
PubMed 27280436 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.34 9.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4471466 1 9.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4471466 Ki = 0.46 nM 9.34