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Assay Detail

CHEMBL4426140

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]HU-243 from rat CB2 receptor expressed in African green monkey COS7 cell membranes after 90 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL2470)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis.
Morales P, Gómez-Cañas M, Navarro G, Hurst DP, Carrillo-Salinas FJ, Lagartera L, Pazos R, Goya P, Reggio PH, Guaza C, Franco R, Fernández-Ruiz J, Jagerovic N.
J Med Chem (2016) 59 : 6753 -6771
PubMed 27309150 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.64 7.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL497392 1 7.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL497392 Ki = 22.7 nM 7.64