Assay Detail
Binding
CHEMBL4426890
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Axl (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein kinase receptor UFO (CHEMBL4895) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
4-Oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as New Axl Kinase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.92 | 7.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3810063 | — | — | 1 | 7.99 |
| CHEMBL3809489 | BEMCENTINIB | 2.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3810063 | — | IC50 | = | 10.3 | nM | 7.99 |
| CHEMBL3809489 | BEMCENTINIB | IC50 | = | 14.0 | nM | 7.85 |