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Assay Detail

CHEMBL4426899

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human CDK11
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 11B (CHEMBL5808)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

4-Oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as New Axl Kinase Inhibitors.
Tan L, Zhang Z, Gao D, Luo J, Tu ZC, Li Z, Peng L, Ren X, Ding K.
J Med Chem (2016) 59 : 6807 -6825
PubMed 27379978 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.33 6.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4571241 1 6.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4571241 Kd = 470.0 nM 6.33