Assay Detail
Functional
CHEMBL4427461
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitubercular activity against oxygen-deprived Mycobacterium tuberculosis H37Rv assessed as bacterial growth inhibition incubated for 5 days under aerobic conditions by LOR assay
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mycobacterium tuberculosis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dehydrozingerone Inspired Styryl Hydrazine Thiazole Hybrids as Promising Class of Antimycobacterial Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| MIC | 2 | - | - |
| IC50 | 2 | 6.92 | 7.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4455126 | — | — | 2 | 7.01 |
| CHEMBL4534306 | — | — | 2 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4455126 | — | IC50 | = | 97.0 | nM | 7.01 |
| CHEMBL4534306 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL4455126 | — | MIC | = | 280.0 | nM | - |
| CHEMBL4534306 | — | MIC | = | 500.0 | nM | - |