Assay Detail
Binding
CHEMBL4428356
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Modulation of gamma secretase (unknown origin) assessed as reduction in amyloid beta levels
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Notch Antagonists: Potential Modulators of Cancer and Inflammatory Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.00 | 4.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL190083 | TARENFLURBIL | 3.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL190083 | TARENFLURBIL | IC50 | = | 100000.0 | nM | 4.00 |