Assay Detail
Binding
CHEMBL4430692
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using fluorogenic substrate by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3086767 | — | — | 1 | 5.30 |
| CHEMBL3086768 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3086767 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3086768 | — | IC50 | = | 5000.0 | nM | 5.30 |