Compound Detail
CHEMBL3086768
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Basic Information
| ChEMBL ID | CHEMBL3086768 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MNMBNWINDLRVJD-UHFFFAOYSA-N |
9
Targets
10
Activities
1
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
250.3
MW (Da)
1.02
ALogP
3
HBA
3
HBD
78.4
PSA (Ų)
0.50
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 10 meas. best 8.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histone deacetylase 2 CHEMBL1937 | IC50 | 8.46 | 6.88 | 3.5 | 2 |
| Histone deacetylase 6 CHEMBL1865 | IC50 | 6.41 | 6.41 | 385.8 | 1 |
| Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) CHEMBL2111363 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
| Histone deacetylase 8 CHEMBL3192 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
| Histone deacetylase 1 CHEMBL325 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
| Histone deacetylase 11 CHEMBL3310 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
| Histone deacetylase 4 CHEMBL3524 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
| Histone deacetylase 9 CHEMBL4145 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
| Polyamine deacetylase HDAC10 CHEMBL5103 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine