Assay Detail
Functional
CHEMBL4430789
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Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.21 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4483393 | — | — | 1 | 5.21 |
| CHEMBL29292 | UBENIMEX | 2.0 | 1 | - |
| CHEMBL4454667 | — | — | 1 | - |
| CHEMBL4576374 | — | — | 1 | - |
| CHEMBL4537106 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4483393 | — | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL29292 | UBENIMEX | IC50 | - | — | - | |
| CHEMBL4454667 | — | IC50 | = | 156200.0 | nM | - |
| CHEMBL4576374 | — | IC50 | = | 103500.0 | nM | - |
| CHEMBL4537106 | — | IC50 | = | 124100.0 | nM | - |