Assay Detail
ADMET
CHEMBL4430792
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MCF10 cells after 72 hrs by SRB assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MCF10 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.40 | 4.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4483393 | — | — | 1 | 4.40 |
| CHEMBL4467841 | — | — | 1 | - |
| CHEMBL4537106 | — | — | 1 | - |
| CHEMBL4455383 | — | — | 1 | - |
| CHEMBL4557950 | — | — | 1 | - |
| CHEMBL4576374 | — | — | 1 | - |
| CHEMBL4454667 | — | — | 1 | - |
| CHEMBL4464704 | — | — | 1 | - |
| CHEMBL4456116 | — | — | 1 | - |
| CHEMBL4435767 | — | — | 1 | - |
| CHEMBL4460083 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4483393 | — | IC50 | = | 40200.0 | nM | 4.40 |
| CHEMBL4467841 | — | IC50 | - | — | - | |
| CHEMBL4537106 | — | IC50 | = | 249100.0 | nM | - |
| CHEMBL4455383 | — | IC50 | - | — | - | |
| CHEMBL4557950 | — | IC50 | - | — | - | |
| CHEMBL4576374 | — | IC50 | = | 1438800.0 | nM | - |
| CHEMBL4454667 | — | IC50 | = | 903600.0 | nM | - |
| CHEMBL4464704 | — | IC50 | = | 897100.0 | nM | - |
| CHEMBL4456116 | — | IC50 | = | 1964800.0 | nM | - |
| CHEMBL4435767 | — | IC50 | - | — | - | |
| CHEMBL4460083 | — | IC50 | = | 3325800.0 | nM | - |