Assay Detail
Functional
CHEMBL4430968
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Advances in rationally designed dual inhibitors of HIV-1 reverse transcriptase and integrase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.52 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL593 | DELAVIRDINE | 4.0 | 1 | 7.68 |
| CHEMBL4587138 | — | — | 1 | 4.44 |
| CHEMBL4461731 | — | — | 1 | 4.44 |
| CHEMBL4525601 | — | — | 1 | - |
| CHEMBL4549316 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL593 | DELAVIRDINE | EC50 | = | 21.0 | nM | 7.68 |
| CHEMBL4587138 | — | EC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL4461731 | — | EC50 | = | 36500.0 | nM | 4.44 |
| CHEMBL4525601 | — | EC50 | = | 163500.0 | nM | - |
| CHEMBL4549316 | — | EC50 | = | 175000.0 | nM | - |