Assay Detail
Binding
CHEMBL4431573
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Dengue virus ribose 2'-O methyltransferase using RNA substrate after 20 mins in presence of [methyl-3H]-AdoMet by microbeta counting analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Dengue virus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Medicinal Chemistry of Dengue Virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.85 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1214186 | SINEFUNGIN | 2.0 | 1 | 7.39 |
| CHEMBL418052 | S-ADENOSYLHOMOCYSTEINE | — | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1214186 | SINEFUNGIN | IC50 | = | 41.0 | nM | 7.39 |
| CHEMBL418052 | S-ADENOSYLHOMOCYSTEINE | IC50 | = | 490.0 | nM | 6.31 |